Immagine
 Trilingual World Observatory: italiano, english, română. GLOBAL NEWS & more... di Redazione
   
 
\\ Home Page : Articolo
More than 50 years ago, NYU-Poly alumni John Gilbert was asked to evaluate a newly- developed material called Teflon. Inspired by teflon, researchers create super durable proteins.
By Admin (from 18/10/2011 @ 08:00:11, in en - Science and Society, read 1315 times)

His experiments using the fluorinated polymer as a surface coating for pots and pans helped usher in a revolution in non-stick cookware. Today, NYU-Poly Assistant Professor of Chemical and Biological Sciences Jin Montclare is taking the research theme in a new direction, investigating fluorinated proteins -- a unique class of proteins that may have a wide range of applications from industrial detergents to medical therapeutics.

In a paper published in the current issue of ChemBioChem, Montclare and Peter Baker, who just received his doctoral degree from NYU-Poly, detail their success in creating proteins that are considerably more stable and less prone to denaturation than their natural counterparts. These qualities enable them to retain both their structure and function under high temperatures in which other proteins would simply break down.

Inspired by teflon, researchers create super durable proteins

Fluorinated amino acids (p-fluorophenylalnine highlighted in the interface) help stabilize Teflon-like proteins against heat inactivation, allowing them to function more robustly, even at elevated temperatures.

Inspired by the ability of fluorinated polymers like Teflon to stabilize surfaces, Montclare and Baker set their sights on developing a process that would allow them to reinforce the interface of proteins, rendering them more resistant to degradation.

“One of the main challenges of proteins—whether they’re in the body or in the lab—is that they are naturally created to function under specific conditions, and to break down under others,” Montclare explained. “A stable protein that was still active and functional under a variety of conditions would open up an extraordinary range of potential for scientists and product developers.”

Through a trick of genetic engineering, the scientists were able to coax a strain of bacteria into taking up amino acids—the building blocks of protein—that were chemically altered by the addition of fluorine. “Nature doesn’t make fluorinated amino acids, but these experiments show that we can create them,” said Montclare. The result was a "fluorinated" protein that can withstand temperatures up to 140 degrees Fahrenheit with no compromise in activity or function.

Next up for Montclare and Baker are experiments to test the limits of their success in creating fluorinated or Teflon-like proteins. They’re hoping that this type of effect can be achieved with a wide range of proteins, especially those used in medicine including some therapeutic cancer drugs. The stable proteins may also some day act as prophylactics to combat exposure to neurotoxic agents (including warfare agents)–something that is of interest to the Department of Defense. The scientists hope to improve the proteins’durability and decrease the need for precise storage conditions, which often include refrigeration to prevent breakdown.

Source: PhysOrg

Articolo Articolo  Storico Storico Stampa Stampa  Share
Cannabis seeds, Autoflowering seeds, Greenhouse, Sweet Seeds, Dutch Passion
comments powered by Disqus
 
Nessun commento trovato. No comments found. Nici un comentariu găsit.

Anti-Spam: dial the numbers CAPTCHA
Text (max 5000 characters)
Nome - Name - Nume
Link ( OPTIONAL - visible on the site - NOT a must )


Disclaimer
Tuo commento sarŕ visibile dopo la moderazione. - Your comment will be visible after the moderation. - Comentariul tău va fi vizibil după moderare.
Ci sono 3268 persone collegate

< luglio 2019 >
L
M
M
G
V
S
D
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
       
             

Titolo
en - Global Observatory (605)
en - Science and Society (594)
en - Video Alert (346)
it - Osservatorio Globale (503)
it - Scienze e Societa (555)
it - Video Alerta (132)
ro - Observator Global (399)
ro - Stiinta si Societate (467)
ro - TV Network (149)
z - Games Giochi Jocuri (68)

Catalogati per mese - Filed by month - Arhivate pe luni:

Gli interventi piů cliccati

Ultimi commenti - Last comments - Ultimele comentarii:
Hi, it's Nathan!Pretty much everyone is using voice search with their Siri/Google/Alexa to ask for services and products now, and next year, it'll be EVERYONE of your customers. Imagine what you are ...
15/01/2019 @ 17:58:25
By Nathan
Now Colorado is one love, I'm already packing suitcases;)
14/01/2018 @ 16:07:36
By Napasechnik
Nice read, I just passed this onto a friend who was doing some research on that. And he just bought me lunch since I found it for him smile So let me rephrase that Thank you for lunch! Whenever you ha...
21/11/2016 @ 09:41:39
By Anonimo


Titolo

Latest NEWS @
www.TurismoAssociati.it

Non-Hodgkin lymphoma cured by CANNABIS. The video of Stan and Barb Rutner.

Dr. Joycelyn Elders, U.S. surgeon general: Myths About Medical Marijuana in The Providence Journal, 2004.

Marihuana vindeca CANCERUL: marturii despre uleiul de cocos si canabis.

Yahoo Incorporated Mail. My account recovery information is incorrect. The Password Helper says my password can't be reset online. "First time signing in here?" message.

All information in a video about Donatio Mortis Causa and The Venus Project

What is TOR browser?

Britain weighs response to Iran Gulf crisis with few good options

Factbox: Strait of Hormuz: the world's most important oil artery

Timeline: Iran's recent clashes with the West over Gulf shipping, nuclear plans

Japan's pro-constitution reform forces fall short of two-thirds upper house majority: NHK

Triad gangster attack in Hong Kong after night of violent protests: lawmaker

Puerto Rico governor refuses to resign as island braces for big protest

Ultimele articole - Antena3.roHOROSCOP. Sfatul Arhanghelului Mihail pentru zodii 22 iulie. Scorpionii sunt ajuta?i de îngerii iubirii, Pe?tii trebuie sa aiba încredere

HOROSCOP 22 IULIE. Capricornii sunt foarte ocupa?i la munca, Gemenii au parte de o zi stralucitoare

CALENDAR ORTODOX 22 IULIE. Ce sfânta mare sarbatorim astazi

În acest sat din România, localnicii cred ca sunt proteja?i de un sfânt. „E o adevarata minune ce se întâmpla aici!”

Reactia dura a unui italian care a facut sase ore de la Bucuresti pâna la Castelul Bran: „Când am ajuns acolo, ne-a pierit tot cheful de vizitat”

LOTERIA BONURILOR FISCALE. Bonurile fiscale câ?tigatoare extrase duminica, 21 iulie





22/07/2019 @ 05:21:21
script eseguito in 775 ms