Immagine
 Trilingual World Observatory: italiano, english, română. GLOBAL NEWS & more... di Redazione
   
 
\\ Home Page : Articolo
Patients who suffer from chronic heart failure may be protected by marijuana-activated pathways, according to a recent study.
By Admins (from 02/02/2014 @ 07:04:31, in en - Global Observatory, read 1500 times)

Investigators from China, Japan and Belgium observed a link between CB1 receptors – pathways in the brain responsible for the marijuana high – and survival rates in mouse models of chronic heart failure.

Mice that had low levels of CB1 receptors were more likely to die and suffered greater heart abnormalities than mice with healthy CB1 levels.

The findings were published in the September issue of the International Journal of Cardiology.

In this study, we found that CB1 deficiency contributed to the exacerbation of chronic cardiac remodeling… revealing a new role of CB1 in pathophysiology of CHF [chronic heart failure].

According to the authors, CB1 receptors have been shown in previous studies to play an important role in a variety of cardiovascular functions.

CB1 activation has been reported to regulate cardiovascular function in hypertension, inhibit the release of neurohormonal factors, improve myocardial energy metabolism, and suppress vasopressin-induced vasoconstriction.

Likewise, the authors note that CB1 stimulation helps to dampen activity of the sympathetic nervous system, which is known to exacerbate problems associated with chronic heart failure.

This, they suggest, may explain why mice without CB1 receptors experienced more progressive heart failure than healthy mice.

While CB1 receptors are stimulated by compounds in marijuana like THC, they also interact with natural marijuana-like chemicals produced by the body (endocannabinoids).

Because of this, the authors believe the body’s cannabinoid system may play a broader role in cardiac function – beginning at the earliest stages of life.

Since endogenous cannabinoids and CB1 receptors are present from the early stages of gestation and play a number of vital roles for the developing organism, our results implicated that endogenous cannabinoid release contributes to the heart development in pre or postnatal life.

However, the authors say there are still “many unsolved problems” when it comes to cannabinoids and heart function, with other research providing conflicting results on whether they are truly helpful or harmful.

While further studies will hopefully provide scientists with clearer answers, the authors conclude that “proper” activation of CB1 receptors appears to be protective in chronic heart failure.

No sources of funding were reported

Source: LeafScience.com

Articolo Articolo  Storico Storico Stampa Stampa  Share
Cannabis seeds, Autoflowering seeds, Greenhouse, Sweet Seeds, Dutch Passion
comments powered by Disqus
 
Nessun commento trovato. No comments found. Nici un comentariu găsit.

Anti-Spam: dial the numbers CAPTCHA
Text (max 5000 characters)
Nome - Name - Nume
Link ( OPTIONAL - visible on the site - NOT a must )


Disclaimer
Tuo commento sarŕ visibile dopo la moderazione. - Your comment will be visible after the moderation. - Comentariul tău va fi vizibil după moderare.
Ci sono 1709 persone collegate

< febbraio 2020 >
L
M
M
G
V
S
D
     
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
 
             

Titolo
en - Global Observatory (605)
en - Science and Society (594)
en - Video Alert (346)
it - Osservatorio Globale (503)
it - Scienze e Societa (555)
it - Video Alerta (132)
ro - Observator Global (399)
ro - Stiinta si Societate (467)
ro - TV Network (149)
z - Games Giochi Jocuri (68)

Catalogati per mese - Filed by month - Arhivate pe luni:

Gli interventi piů cliccati

Ultimi commenti - Last comments - Ultimele comentarii:
Hi, it's Nathan!Pretty much everyone is using voice search with their Siri/Google/Alexa to ask for services and products now, and next year, it'll be EVERYONE of your customers. Imagine what you are ...
15/01/2019 @ 17:58:25
By Nathan
Now Colorado is one love, I'm already packing suitcases;)
14/01/2018 @ 16:07:36
By Napasechnik
Nice read, I just passed this onto a friend who was doing some research on that. And he just bought me lunch since I found it for him smile So let me rephrase that Thank you for lunch! Whenever you ha...
21/11/2016 @ 09:41:39
By Anonimo


Titolo

Latest NEWS @
www.TurismoAssociati.it

Non-Hodgkin lymphoma cured by CANNABIS. The video of Stan and Barb Rutner.

Dr. Joycelyn Elders, U.S. surgeon general: Myths About Medical Marijuana in The Providence Journal, 2004.

Marihuana vindeca CANCERUL: marturii despre uleiul de cocos si canabis.

Yahoo Incorporated Mail. My account recovery information is incorrect. The Password Helper says my password can't be reset online. "First time signing in here?" message.

All information in a video about Donatio Mortis Causa and The Venus Project

What is TOR browser?

Coronavirus on G20 agenda as China reports uptick in cases

Nissan, Honda delay restart of some China plants due to coronavirus

Factbox: Events affected by coronavirus epidemic

Iran holds parliamentary election likely to bolster hardliners

Northwest China's Gansu lowers coronavirus emergency response level

Assange's fate hangs in balance as UK court considers U.S. extradition bid

Ultimele articole - Antena3.roMo?ii de iarna 2020. Tradi?ii ?i obiceiuri. Ce se da de pomana în Sâmbata mor?ilor

Alocatiile pentru copii ar putea fi diferentiate în functie de veniturile familiei - proiect

Georgian Ene a murit împu?cat în Italia, în timpul unui jaf. În România, prietenii îl vad ca pe un „Robin Hood”

Ponta, dupa anun?ul lui Raed Arafat privind privatizarea sanata?ii: Va trata?i acasa ca în Evul Mediu? Sa nu spune?i ca nu a?i ?tiut

Economistul Ben?a, predic?ie dura pentru români dupa prabu?irea leului: Efectele deprecierii monedei na?ionale

Raed Arafat, semnal de alarma privind privatizarea din Sanatate: O vizita la UPU ar putea costa 10.000 de lei!





21/02/2020 @ 09:15:19
script eseguito in 886 ms