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Di seguito tutti gli interventi pubblicati sul sito, in ordine cronologico.
Un passo importante, che fissa la corretta interpretazione della normativa sulle droghe. Incapaci di produrre una innovazione politica all'altezza del mutato contesto internazionale, in Italia il testo unico sulle droghe viene rivisto e riscritto dalla giurisprudenza, ieri dalla Corte di cassazione, l'altro ieri dalla sentenza con cui la Corte costituzionale ha giudicato illegittima l'intera legge Fini-Giovanardi. Potrebbero tranquillamente riferirvisi le argomentazioni usate da Stefano Rodotà su la Repubblica di domenica scorsa a proposito della procreazione medicalmente assistita: "negli ultimi venti anni la tutela dei diritti è stata garantita quasi esclusivamente dai giudici costituzionali e ordinari, mentre il Parlamento cercava di ridurne illegittimamente l'ampiezza o rimaneva colpevolmente silenzioso". Un bel paradosso e il principale dei problemi per chi, come il Ministro Orlando, voglia riformare la giustizia nel solco della distinzione di ruoli tra politica e magistratura: se la politica continua a non decidere, o a decidere in senso contrario ai vincoli posti dalla Costituzione, come pretendere che non vi sia un conflitto con una giurisdizione cui sono delegate tutte le possibilità di riconoscimento dei diritti dei cittadini?
Non altro è il problema che abbiamo posto negli ultimi vent'anni in materia di droghe, sin dal referendum del 1993, che abrogò le parti più ideologiche e repressive della legge Iervolino-Vassalli, e poi qualche mese fa, all'indomani della abrogazione della legge Fini-Giovanardi. Spetta al Parlamento riscrivere da cima a fondo la legge sulla droga, tenendo conto del fallimento della war on drugs, del mutato contesto internazionale e dei cambiamenti nell'uso delle sostanze stupefacenti. E spetta al Parlamento risolvere i problemi di carattere generale sollevati da un corretto esercizio del potere giurisdizionale. Tra questi, quello delle migliaia di persone tutt'ora in carcere in forza di previsioni penali giudicate illegittime dalla sentenza della Corte costituzionale del febbraio scorso.
La perdurante ignavia del Parlamento – interrotta solo dal tentativo revanchista della Ministra Lorenzin, di reintrodurre per decreto l'intera legge Fini-Giovanardi (norme penali comprese) – ci ha costretto a riprendere la via giudiziaria. E' possibile tollerare ulteriormente il prolungarsi dell'esecuzione di pene giudicate, nella loro misura, illegittime dalla Corte costituzionale? La Corte di cassazione ha chiaramente detto di no, ma questo non basta quando il problema sia polverizzato in migliaia di situazioni personali che richiedono ricorsi individuali al giudice dell'esecuzione, ed essendo la gran parte degli interessati privi della minima cognizione giuridica e di un'adeguata assistenza legale. Tocca allora andare città per città e carcere per carcere, a informare i detenuti e spiegare loro che possono chiedere la rideterminazione della pena e, molto probabilmente, essere scarcerati. E' quello che stiamo facendo, con i garanti dei detenuti, le camere penali e le altre associazioni che hanno aderito alla campagna "Cancellare le pene illegittime". In Friuli, dove la campagna è stata presentata alla stampa il 2 agosto scorso, potrebbero essere 262 su 644 i detenuti interessati al ricalcolo delle pene, a Ferrara 50 su 300. Interessa al Ministro Orlando e ai riformatori della giustizia e delle istituzioni questa riaffermazione in concreto di principi basilari dello stato di diritto?
Fonte: FuoriLuogo.it
Umberto Veronesi, da sempre a favore della liberalizzazione delle cosiddette 'droghe leggere', che interviene così sul tema sul numero del settimanale 'Oggi'.
"La marijuana fa male? Come ministro della Salute, quando ricoprii l'incarico anni or sono, mi posi anch'io questa domanda - ricorda il direttore scientifico dell'Istituto europeo di oncologia di Milano - E me la posi anche come medico e soprattutto come padre di famiglia. Ebbene, la commissione scientifica che avevo nominato concluse che i cosiddetti 'danni da spinello' sono praticamente inesistenti. Dopo quella, altre commissioni scientifiche giunsero alle stesse conclusioni. E oggi perfino l'Organizzazione mondiale della sanità ha invitato i governi a depenalizzare l'uso personale di marijuana, consapevole su dati scientifici che l'uso di spinelli non fa male".
Nella sua rubrica lo scienziato definisce "infondata anche la credenza che la marijuana dia dipendenza e apra la strada all'uso delle droghe pesanti, come cocaina e morfina. Liberalizzare lo spinello non è malinteso permissivismo, ma una posizione realistica che punta alla riduzione del danno. Risulta che metà dei nostri giovani e molti adulti fanno uso di marijuana. Ha senso criminalizzarli?".
Fonte: AdnKronos Salute
Neuropathic and inflammatory pain
Nociception (pain perception) is a critical mechanism of the body self-defence, inducing to discontinue a stimuli potentially deteriorating.
When pain is experienced chronically,often as a consequence of a neural or metabolic dysfunction, as in the case of neuropathic pain (NP), it is fundamental to find agents able to target the pathways producing allodynia (sensation of pain evoked by a stimulus which would not, normally, produce it) and ultimately to eradicate them. [1]
It has been estimated that 7-8% of the entire population of Western Countries develops neuropathic pain, which is often caused by other pathologies (cancer, diabetes, Multiple Sclerosis, HIV or stroke, just to mention a few).[2]
Despite the aetiology of the disease is multifarious, it causes the nervous system to be hypersensitised due to prolonged impulses.
Neuropathic pain alone is a chronic debilitating disease that affects up to 4 million people just in Europe; given the poor outcome of the medicines currently in use for the management of symptoms, (gabapentin, opioids and tricyclic antidepressant mainly) many studies are focussed on this field of study. [3]
Why using cannabinoids?
Phytocannabinoids have been extensively used throughout history for various therapeutic purposes, particularly analgesic. However, the cannabinoid circuitry is relatively young, with only 20 years since its first characterization by the pioneering studies of Raphael Mechoulam, whose discoveries conveyed these chemicals from traditional home remedies to pharmacological investigation. [4]
Since the discovery of Cannabinoid receptors pain regulation became one of the main area of study. Compelling evidence has shown that cannabinoids decrease allodynia both thermal and mechanical, proving their role for treating neuropathic pain. [5]
Cannabinoids vs opioids
The main mediator of the antinociceptive effect is thought to
be the cannabinoid CB1 receptor. The benefit of targeting directly CB1 receptors is endorsed by their anatomical distribution in core pain centers of the brain (Periaqueductal grey-substantia gelatinosa-medulla oblongata-dorsal horn). [6]
CB1 agonists (all the drugs that activate CB1 receptors, such as THC) prevent “wind-up” phenomenon in the dorsal horn (an exaggerated sensitization to pain leading to allodynia and hyperalgesia and hallmark of neuropathic pain). (Hyperalgesia =increased sensation to pain, usually due to damaged pain receptors and nerve terminals)
It is hence crucial to pinpoint that manipulating cannabinoid circuitry is more advantageous than targeting directly opioids for the treatment of neuropathic pain. [6, 7]
Moreover, the medicines that activate CB1 receptors maintain their efficacy, at the opposite of morphine, which is less potent over time (so that more doses are needed, and with it, an increase in side effects).
Importantly, the spontaneous discharge (which lead to pain sensation) has been located mainly in primary afferent myelinated A-fibres, which are rich in cannabinoid receptors rather than opioids. [8]
The current medications for treating pain are still mainly opioids, but only approximately 50% of the sufferers finds relief with the available cures, thus highlighting how the clinic would greatly benefit from drugs oriented on cannabinoids modulation. [2]
On the ring today...
Opioids are prescribed worldwide to deal with pain.
Only recently Sativex has been approved for treatment of pain in 2 Countries only! If you want to know more click here.
Here are some facts, all the side effects, both very common and rare for both medications.
Remember that researching cannabinoids medications does not necessarly mean using THC-based medications and lots of research is going through in this direction, making cannabinoid-based drugs even safer and non-psychoactive.
| Side effects |
Cannabis |
Morphine |
| |
|
blood pressure chages |
| |
|
constriction of the pupil of the eye |
| |
|
irregular heart rate |
| |
increased heart rate |
erectile dysfunction |
| Cardiovascular |
redness of the eyes |
eye or eyesight problems |
| |
vasodilatation/facial flush |
facialflushing |
| |
|
irregular heart rate |
| |
|
oedema of the extremities |
| |
|
palpitations |
| |
|
|
| |
aids sleeping |
difficult sleeping |
| Circadian |
somnolence |
sleepiness |
| |
|
|
| |
aids gastrointestinal functions (diarrhea is rare) |
biliary problems |
| Gastrointestinal |
anti-emetic, can cause nausea when overdosed |
constipation |
| |
eases cramps |
gastrointestinal problems |
| |
abdominal pain can occur (rare) |
indigestion |
| |
|
nausea |
| |
|
vomiting |
| |
|
stomachpain |
| |
|
|
| |
|
amenorrhoea |
| Hormonal |
|
decreased libido |
| |
|
|
| |
|
allergic reactions |
| |
|
anaphylactic reactions |
| Immunologic |
anti-inflamatory |
itching |
| |
|
skin rash or rashes |
| |
|
worsening of pancreatitis |
| |
|
urticaria |
| |
|
|
| Muscolar |
muscle relaxant |
abnormal muscle movement |
| |
unsteadiness |
muscle twitching |
| |
|
|
| |
|
confusion |
| |
|
drowsiness |
| |
|
headaches |
| |
|
loss of appetite |
| |
|
thinking problems |
| |
|
weakness |
| |
confusion |
convulsions |
| |
drowsiness |
dysphoria- euphoria |
| |
increased appetite |
fainting |
| |
weakness |
feeling agitated |
| Neurologic |
euphoria |
general feeling of being unwell |
| |
sense of well-being |
hallucinations |
| |
depersonalization |
mood changes |
| |
hallucination |
physical dependence |
| |
paranoid reaction |
psychological dependence |
| |
|
vertigo |
| |
|
withdrawal symptoms |
| |
|
|
| |
|
bronchospasm |
| Respiratory |
bronchodilator |
pulmonary oedema |
| |
|
respiratory depression |
| |
|
|
| |
|
severe dry mouth |
| |
|
sweating |
| Salivation |
dry mouth |
renal spasms |
| |
|
urinary retention |
List of references:
1. Scadding, J. (2003). Neuropathic Pain.ACNR. 3 (2), 8-14.
2. Mao, J., Price, D.D., Lu, J., Keniston, L., Mayer, D.J. (2000) Two distinctive antinociceptive systems in rats with pathological pain. Neurosci. Lett., 280, 13-16.
3. Selph, S Carson, S Fu, R et al. (2011). Drug Class Review Neuropathic Pain. Available: ncbi.nlm.nih.gov . Last accessed 4/3/13 .
4. British Medical Association (1997) Therapeutic Uses of Cannabis. London, Harwood Academic Publishers
5. Fox, A., Kesingland, A., Gentrym C., McNair, K., Patel, S., Urban, L., James, I. (2001) The role of central and peripheral Cannabinoid 1 receptors in the antihyperalgesic activity of cannabinoids in a model of neuropathic pain. Pain, 92, 91-100.
6. Martin, B.R., Lichtman, A.H. (1998) Cannabinoid transmission and pain perception. Neurobiol.Dis., 5, 447-461.
7. Lichtman, A.H., Martin, B.R. (1991) Spinal and supraspinal components of cannabinoid-induced antinociception. J.Pharmacol. Exp. Ther., 258, 517-523.
Author: Viola Brugnatelli, BSc Neuroscience - Source: Casey McClain at naturegoingsmart.com/
I made this over the weekend and it was SPECTACULAR! I love chicken salad though. If you even like chicken salad you'll love this.
Ingredients:
3 large chicken breasts, cooked and diced 1/4 cup celery, diced 1/4 cup fresh red pepper, diced 1/4 cup onion, diced 1/3 cup CannaMayo 1 tablespoon fresh rosemary chopped, salt and pepper to taste.
Directions:
Mix all of the ingredients together.
Serve immediately or keep cold in the refrigerator.
This is the last time I'll send you the link below for awhile.
It's a great place and it's where I get all of my stuff so I want to make sure you know about it. Have a great day...
Source: CookingWithCannabis
This is delicious, you must try it.
Ingredients:
Baking spray
2 sticks canna-butter, room temperature, or use less medicated butter and more without cannabis
2 & ˝ cups sugar, divided into 2 cups and ˝ cup
2 large eggs, lightly beaten
2 cups (1 pint) sour cream
1 tablespoon vanilla
2 cups all purpose flour
1 tablespoon baking powder
Ľ teaspoon salt
1 cup walnuts, chopped
1 cup chocolate chips
1 tablespoon cinnamon
˝ teaspoon ground cardamom
Directions:
One of the great edible pleasures in life is a moist piece of buttery cinnamon coffee cake with just the right amount of streusel and swirl; two easy baking steps to master. This cake has been present for every one of our News Year's Day breakfasts for over 14 years. It didn't always have a boatload of weed in it, as it does in this recipe, but when I thought of foods that would be perfect when medicated this came quickly to mind. It's
pretty easy to make. Lots of butter, so a perfect recipe for a medicated make-over. When cooking with marijuana, you need fat (butter, all cooking oils, milk products that are not non-fat) because the THC will cling to the fat when heated. So, for example, if you make hot cocoa, and you use non-fat milk, the potency will be radically different than if you used 2% or whole milk.
Back to the cake. There is something very comforting about a coffee cake. This one has a good amount of vanilla, chocolate chips and walnuts, and a tasty streusel topping that has a touch of cardamom and healthy dose of cinnamon. It is super with a cup of coffee or tea, and is not half bad with a scoop of ice cream nested on the top. One of the local shops in my town does a cardamom ice cream that when placed on the top of a slice of this the cake causes great sighs, swoons and smiles due to the high level of deliciousness!
Heat oven to 325.
Spray a 9 x 13 inch baking pan.In a small bowl, mix 1/2 cup of the sugar with the walnuts, chocolate chips, cinnamon and cardamom. Set aside. In a large mixing bowl cream together the butter and 2 cups of sugar. Add eggs, blending well, then the sour cream and vanilla.Sift the flour, baking powder, and salt. Fold the dry ingredients into the creamed mixture, and beat until just blended.
Do not overbeat. Pour one-third of the batter into the prepared pan.
Sprinkle with half of the nut/chocolate mixture. Repeat. Then add remaining batter.Bake until the center of the cake is set, about 50-60 minutes. A cake tester or toothpick inserted in the center should come out clean. Oven temps can vary quite a bit, so please check for doneness after 45 minutes, it's a bummer if this delicious cake is overcooked.
Check out the link below for some awesome information...
Source: CookingWithCannabis
Real Pot Pie
Ingredients:
1 pound skinless, boneless chicken breast halves - cubed
1 cup sliced carrots
1 cup frozen green peas
1/2 cup sliced celery
1/3 cup cannabutter
1/3 cup chopped onion
1/3 cup all-purpose flour
1/2 teaspoon salt
1/4 teaspoon black pepper
1/4 teaspoon celery seed
1 3/4 cups chicken broth
2/3 cup milk
2 (9 inch) unbaked pie crusts
Prep time: 20 mins
Cook: 50 mins
Ready in: 1hr 10mins
Directions:
1. Preheat oven to 425 degrees F (220 degrees C)
2. In a saucepan, combine chicken, carrots, peas, and celery.
Add water to cover and boil for 15 minutes. Remove from heat, drain and set aside.
3. In the saucepan over medium heat, cook onions in Cannabutter until soft and translucent. Stir in flour, salt, pepper, and celery seed. Slowly stir in chicken broth and milk. Simmer over medium-low heat until thick. Remove from heat and set aside.
4. Place the chicken mixture in bottom pie crust. Pour hot liquid mixture over. Cover with top crust, seal edges, and cut away excess dough. Make several slits in the top to allow steam to escape.
5. Bake in the preheated oven for 30-35 minutes, or until pastry is golden brown and filling is bubbly. Cool for 10 minutes before serving.
Check out the link below...
Source: CookingWithCannabis
They aren't potatoes but fried malanga, which is like a potato but less acidic. Don't ask what Hialeah has to do with it.
You'll never know unless you've been there.
Ingredients:
Some fresh malangas, chopped and/or grated
A few eggs
A pound of hash butter, or however much you need
Salt, pepper and garlic to taste
Directions:
Beat the eggs, then add the salt, pepper, garlic and malanga to form a thick paste. Refrigerate for one hour. Melt and heat the hash butter in a saucepan over the stove. Take out the malanga paste, roll into balls and drop into the heated butter and let them fry until crispy. Click below for more recipes...
Source: CookingWithCannabis
Ingredients:
1 1/2 cups fresh raspberries
1/4 cup water
1 tablespoon lemon juice
1/4 cup CannaHoney
1 cup Cannabis Almond Milk (or other milk)
1/4 cup plain yogurt
2 tablespoons sugar
1 1/2 cups fresh blueberries
1 tablespoon lime juice
Directions:
Puree the raspberries, water and lemon juice together in a blender. Add 1/8 cup CannaHoney halfway through, continue blending until smooth.Pour raspberry puree through sieve and into a clean bowl. Discard seeds.Fill each popsicle mold 1/3 the way full with raspberry puree.Freeze popsicles for 1 hour. Mix Cannabis Almond Milk, yogurt and sugar together.Remove the molds from the freezer and fill each mold another 1/3 of the way with yogurt mixture. Freeze popsicles for 1 hour.Puree the blueberries, 1/8 cup water and lime juice together. Add 1/8 cup CannaHoney halfway through, continue blending until smooth. Pour blueberry puree through sieve and into a clean bowl. Discard seeds. Remove the molds from the freezer and insert a popsicle stick through the yogurt layer of each popsicle.Fill the molds with the blueberry puree, leaving a little room at the top (less than 1/2 an inch). Return to freezer and freeze until solid. Usually about 2 hours. Run molds under warm water before opening to loosen popsicles.
Click the link below for more cool stuff...
Source: CookingWithCannabis
Ingredients:
1/2 to 1 stick cannabis butter, depending on potency 4 large potatoes, peeled
1 bunch garlic
1 cup shredded cheddar cheese
1/2 cup sour cream salt, pepper to taste dash of olive oil (to roast garlic)
Directions:
First you will want to prepare the roasted garlic. Cut the top off of the bunch and drizzle about a tbsp of olive oil into the garlic.
Wrap in foil and bake in the oven for 40-50 mins. Garlic should be tender and come apart with a fork.
While you wait for the garlic to cook, cut the peeled potatoes into cubes and boil them in salted water until tender. Drain the potatoes and mash in a big mixing bowl. Add the cannabis butter, allowing to melt and mix in thoroughly. Then add the sour cream, cheese, roasted garlic, salt and pepper and mix together. Makes about six servings, serve immediately. Enjoy!
Check out this link for more healthy cooking tips...
Source: CookingWithCannabis
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