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The Mothership: Enter the mothership, a missing spacecraft and uncover its secrets.

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Researchers from the University of British Columbia's School of Social Work have found that children living in homes where marijuana is grown show no noticeable health differences than those living in the average home.

The study, published in September 2013 in the International Journal of Drug Policy, was led by Janet Douglas, Ph.D, who has spent over 20 years as a child protection social worker in B.C. About a dozen of those years involved responding to cases of children living in marijuana grow-ops.

She believes the findings should serve as guidelines for social workers responding to similar cases.

"If we're going to say that children are at risk living in marijuana grow operations, then we need to be clear what those risks are. If there are no apparent health risks, then we need to scratch that off our list and not say that that's our concern if in fact we have no evidence to show that living in a grow-op impacts a child's health."

Dr. Douglas says the findings came as a surprise, since her experience led her to believe that grow-ops pose a number of health risks to children. Unsafe equipment involved with marijuana cultivation as well as molds and other air contaminants were some of her major concerns.

However, when Dr. Douglas and her colleague compared the relative health of children living in grow-ops, they found no significant differences in the amount of drugs prescribed for these children compared to their peers. Prescription data was gathered on 181 children living in grow-ops and 500 children in the comparison group.

"As far as a child welfare perspective, we just need to understand what our grounds for intervention are," says Dr. Douglas. "If these children are not at risk for health matters, then we need to not say that that's our grounds."

The study received funding from MITACS, BC Mental Health and Addictions Research Network, the BC Child and Youth Health Research Network and BC Ministry for Children and Family Development

Source: LeafScience.com

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18 Wheeler: This game is about you learning to drive a big 18 wheeler truck, maneouvering through various cources and obstacles. Finishing each lesson/level within the allocated time in order to proceed, Tons of Levels, tonnes of fun.

 

Controls: Keyboard Cursor keys.

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Published in the journal Inflammatory Bowel Diseases, the study shows that the majority of IBD patients who try medical marijuana find it "very helpful" for relief of common symptoms, including abdominal pain, nausea and diarrhea.

The research was conducted at an academic medical center at Boston's Brigham and Women's Hospital, and involved a total of 292 patients with IBD. The authors wrote:

"A significant number of patients with IBD currently use marijuana. Most patients find it very helpful for symptom control, including patients with ulcerative colitis, who are currently excluded from medical marijuana laws."

Interestingly, while a large portion of patients in the study reported never trying marijuana, about half of those who never tried it said they'd be interested if it were legally available.

The authors note that "clinical trials are needed" to confirm whether marijuana is indeed helpful, since the study was only based on patients' reports.

Indeed, while animal studies suggest that marijuana could be useful in IBD, only a single small-scale human study has been done so far.

Published earlier this year by researchers at Israel's Tel Aviv University, the study found that 5 of 11 patients with Crohn's disease achieved "complete remission" after eight weeks of medical marijuana treatment. In comparison, only 1 of 10 patients in the placebo group went into remission.

The only human trial achieved complete remission in 5 of 11 Crohn's patients

The study also noted that marijuana seemed to improve appetite and sleep, and helped some patients wean themselves from steroid medications.

Steroids are commonly used to treat IBD, but can cause dependency as well as severe side effects.

But despite recommending that doctors consider marijuana for patients that aren't responding to traditional treatments, the Israeli scientists agree that larger studies are necessary before medical marijuana can be widely recommended as a treatment for IBD.

The Brigham and Women's Hospital study was published ahead of print. No sources of funding were reported

Source: LeafScience.com

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Crash Down: Try to eliminate rows of the same color, but if it builds up too much you will lose the game.

Controls: Mouse: Use your mouse pointer to left-click on 3 or more of the same colored squares to remove them from the group.

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While anecdotal reports support the benefits of medical marijuana in treating the disorder, evidence from clinical research has been lacking.

But now, scientists from the University of Michigan, Harvard Medical School and the University of Illinois at Chicago have confirmed that THC affects the storage and extinction of fearful memories in human subjects.

Published in October 2013 in the journal Neurobiology of Learning and Memory, the team suggests that marijuana pathways in the brain, which make up the cannabinoid system, could be a target for future PTSD treatments.

"Ultimately, the cannabinoid system may serve as a promising target for innovative intervention strategies in PTSD and other fear learning-related disorders."

In the study, researchers performed brain scans on 14 healthy individuals, who were given THC pills (Marinol) or a placebo before being exposed to a fearful stimulus. After 24 hours, individuals who received THC showed increased activity in areas of the brain involved with overcoming past negative memories.

While animal studies also support a role of cannabinoids in overcoming bad memories, the authors note the study was the first to show this effect in humans.

"Together, these findings provide the first evidence that pre-extinction administration of THC modulates the underlying neural circuits involved in fear extinction in humans."

The authors conclude: "these results prompt future investigation to test if cannabinoid agonists can rescue or correct the impaired behavioral and neural function during extinction recall in patients with PTSD."

The study received funding from the National Center for Research Resources and the National Institute of Mental Health

Source: LeafScience.com

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Game Instructions: Use the mouse to create a ring around as many fish as you can that are of the same color. When a valid ring is made the bigger fish will gobble up the smaller one(s), growing even bigger...! You will advance to the next level only when there is one large fish left of each color. Please note that each level is timed... Good Luck!!!

Fish Eat Fish: Capture all the fishes of the same color by trapping them inside a region, drawn on the screen. Highly addictive and must play!

Controls: Mouse.

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Dr. Sean McAllister, of the California Pacific Medical Center (CPMC), has spent nearly a decade studying the effects of cannabidiol – a chemical found in marijuana – on aggressive types of breast and brain cancer.

His research has already shown that cannabidiol (CBD) can reduce the spread of cancer to other parts of the body. Although, so far, he's only been able to study animal and cell culture models. Now he says his team is ready to prove it in humans.

"We are trying to initiate clinical trials in the US. We have designed the trials for breast and brain cancer but are still trying to raise the money for the trials."

Since last year, Dr. McAllister has been going through the difficult and lengthy process of initiating clinical trials. With study designs complete, funding seems to be the only obstacle that remains.

If all goes as planned, he hopes to see CBD being trialed in cancer patients "a year from now."

But it's not only Dr. McAllister that sees promise in cannabis for cancer. A drug company called GW Pharmaceuticals is also trying to study a cannabis-based drug, Sativex, as an add-on treatment for glioblastoma – the most common and deadly form of brain cancer.

The company has already begun recruiting patients for the first phase of clinical trials in Europe. Researchers will first have to prove its safety in a small group of glioblastoma patients before they can start evaluating Sativex's effectiveness at fighting cancer.

According to Dr. McAllister, preclinical research suggests that cannabinoids, while effective alone, may have a greater effect against cancer when combined with current treatments.

"Based on the data, it would be expected that cannabinoids would need to be combined with a first-line agent in order to see the most efficacy in a clinical setting."

Dr. McAllister's breakthrough came in 2007, when his team at CPMC showed that cannabidiol could reduce tumor aggressiveness in breast cancer by "turning off" a protein responsible for the spread of cancer, or metastasis, called Id-1.

Four years later, they were able to confirm the effect in mice, showing that CBD treatment could reduce the number and size of secondary tumors that formed.

Another of his studies, this time in glioblastoma cell cultures, found that CBD and THC could work together to achieve an even greater effect, concluding that "the addition of cannabidiol to Delta(9)-THC may improve the overall effectiveness of Delta(9)-THC in the treatment of glioblastoma in cancer patients."

"You have to build a strong case for clinicians to agree to run clinical trials. We are there now."

While THC also demonstrates anti-cancer potential, Dr. McAllister explains that one of the reasons he chose to study CBD is the lack of psychoactivity – or a high – which could be a concern when conducting studies in humans.

Another obstacle has been gathering enough evidence on the treatment. Despite an abundance of anecdotal reports of cannabis successfully curing cancer, it's taken Dr. McAllister years of effort to "build a strong case" for clinical trials.

But now he says the time has come.

"It takes a significant amount of time to run preclinical experiments," Dr. McAllister explains. "You have to build a strong case for clinicians to agree to run clinical trials. We are there now."

Source: LeafScience.com

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Instructions: your goal is to land accurately right on the platform. Control your ship with the arrow keys. You can slightly increase or decrese the descending of the ship with the up arrow key. Remember, slow down during landing! Good Luck...!!!

Go Green Go: Control your UFO and clear all the levels by landing it accurately on the destination platforms in least possible time.

Controls: Keyboard Arrow keys.

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When it comes to consuming marijuana, the options are vast. Besides rolling a joint, there are a range of pipes and water bongs available on the market. Of course, cannabis can also be used to make various foods and drinks. Topicals and tinctures are popular among medical users as well.

Yet many doctors stand by vaporizers as the ideal method of consuming marijuana. In fact, in Israel, where medical marijuana is legal, vaporizers can be found in hospitals and senior homes. The popular Volcano Medic Vaporizer is also an approved medical device in Canada and the EU.

Here are some major reasons why vaporizers have become so popular among doctors and patients.

1. Lung Health

The effect of vaporizing on the lungs is perhaps the strongest argument for using a vaporizer.

Doctors have long been wary about the use of marijuana as a medicine because of the potential risks of smoking anything. While it's true that smoking marijuana has not been proven to cause lung cancer, the combustion of marijuana still produces several known carcinogens and tar, which can irritate the lungs and lead to chronic bronchitis.

Vaporizers were mainly designed to overcome this issue. By heating marijuana at a lower temperature than combustion, the devices produce an inhalable vapor that still contains the active medical ingredients in marijuana (cannabinoids), but without the harmful by-products.

Vaporizing cannabis is said to remove approximately 95% of the smoke that is inhaled. What's more, vaporizing has been suggested to increase the yield of anti-inflammatory terpenoids that protect the lungs from irritation.

Research also suggests that switching to a vaporizer can reverse respiratory symptoms caused by traditional methods of cannabis intake.

2. Dosing Requirements

Another advantage of vaporizers is the efficiency of converting plant matter into active cannabinoids.

A collaborative study conducted by California NORML and MAPS found that vaporizers could convert 46% of available THC into vapor, whereas the average marijuana joint converted less than 25% of THC.

Likewise, patients ranked vaporizers as the most efficient method of marijuana intake – requiring a lower dose than smoking, edibles and tea – in a recent study published in the Journal of Psychoactive Drugs.

So while vaporizers may be seen as a luxury to some, even the most thrifty marijuana users have realized that the higher efficiency of these devices can eventually offset their initial cost.

3. Side Effects

In the same patient study, vaporizers ranked highest in side effect satisfaction, meaning that patients felt most functional after vaporizing cannabis.

While the study did not investigate specific side effects, some say that vaporizers produce a more clear-headed 'high' due to the lack of smoke inhaled. Cannabis vapor can also be inhaled in short and shallow puffs, whereas other smoking devices may require taking deeper and larger breaths, which can be uncomfortable for novice marijuana users.

Of course, how one reacts to marijuana differs widely from person to person, so vaporizers may not be ideal for everyone. Ultimately, consulting with a healthcare professional and careful experimentation is the best way to figure out what method of marijuana intake is best for you.

Source: LeafScience.com

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Now Colorado is one love, I'm already packing suitcases;)
14/01/2018 @ 16:07:36
By Napasechnik
Nice read, I just passed this onto a friend who was doing some research on that. And he just bought me lunch since I found it for him smile So let me rephrase that Thank you for lunch! Whenever you ha...
21/11/2016 @ 09:41:39
By Anonimo
I am not sure where you are getting your info, but great topic. I needs to spend some time learning much more or understanding more. Thanks for fantastic information I was looking for this info for my...
21/11/2016 @ 09:40:41
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